85-6083-97　CD40 Ligand, Recombinant, Human, aa113-261, His-Tag 10ug　497026

特徴

• CD40 ligand, also known as CD40LG, is a member of the TNF superfamily and is expressed on activated T cells. CD40LG is expressed as a soluble cytokine as well as a homotrimeric type II transmembrane protein. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Mutations in the gene encoding for CD154 are implicated in hyper-IgM immunodeficiency syndrome type 1.
• Recombinant protein corresponding to aa113-261 from human CD40 Ligand/TNFSF5, fused to His-Tag at N-terminal, expressed in E. coli.
• Molecular Weight:~18.3kD
• Biological Activity:Measured by its binding ability in a functional ELISA with Human CD40/TNFRSF5.
• Amino Acid Sequence:＜MGSSHHHHHH SSGLVPRGSH＞ MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LCLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.