85-6054-05　IARS, Recombinant, Human, Met1~Arg500, His Tag, N-terminal (Isoleucyl-TRNA Synthetase protein, IleRS protein, OJ protein) 25ug　553926

特徴

• Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs. [provided by RefSeq]
• Source:Recombinant protein corresponding to IARS, Recombinant, Human, Met1~Arg500, His Tag, N-terminal
• Sequencxe:See Image Library
• Entrez GeneID:3376
• Gene Symbol:IARS
• Gene Alias:FLJ20736, IARS1, ILRS, PRO0785
• Subcellular Location:
CytoplasmPredicted Molecular Mass:
61.7kDAccurate Molecular Mass:
62kD
• Residues & Tags:
Met1~Arg500 with N-terminal His Tag
• Applications:Suitable for use in Positive Control; Immunogen; SDS-PAGE; WB
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Host:E. coli
• Theoretical MW (kD):35.75
• Isoelectric Point:
5.6
• Quality Control:12.5% SDS-PAGE Stained with Coomassie Blue.
• Endotoxin:
≤1.0EU per 1ug (LAL)
• Storage and Stability:Aliquot to avoid repeated freezing and thawing. Store at -70°C. Aliquots are stable for 3-6 months after receipt at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.