85-6052-57　Uridine-5'-methylpropanoate-4-oxime 25mg　CAS No:2349386-89-4　552373

特徴

• EIDD 2801 is an orally bioavailable prodrug of β-D-N4-hydroxycytidine and was shown to inhibit SARS-CoV-2 replication in human airway epithelial cells. EIDD 2801 was also tested in mice infected with SARS-CoV and MERS-CoV viruses. EIDD 2801 targets the RNA-dependent RNA polymerase (RdRp) and reduces virus titer and improved pulmonary function in experimental animals when used in prophylactic and therapeutic regime.
• Synonyms:β-D-N4-Hydroxycytidine-5'-isopropyl ester; EIDD 2801; MK-4482; Molnupiravir
• Molecular Formula:C₁₃H₁₉N₃O₇
• Molecular Weight:329.31
• Appearance:White to off-white powder
• Purity:≥98% (HPLC)
• Identity (1H NMR):Conforms to structure
• Solubility:Soluble in DMSO (25mg/ml), DMF (25mg/ml) or water (2mg/ml).
• Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.