85-6046-43　ABP1/AOC1, Recombinant, Human, aa20-751, His-Tag 50ug　551816

特徴

• ABP1, also known as diamine oxidase (DAO) and amine oxidase copper domain-containing protein 1 (AOC1), is a member of the copper-containing amine oxidase family. This enzyme catalyzes the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. It has an important role in the catabolism of histamine and other bioactive polyamines. Deficiencies in ABP1 can result in histaminosis or dietary histamine intolerance. This protein is also contributed to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer. Recombinant human AOC1, fused to His-Tag at C-terminal, was expressed inHEK293 cell and purified by using conventional chromatography techniques.
• Source:Recombinant protein corresponding to aa20-751 from human ABP1/AOC1 protein, fused to His-Tag at C-terminal, expressed in HEK293 cells.
• AA Sequence:EPSPGTLPRK AGVFSDLSNQ ELKAVHSFLW SKKELRLQPS STTTMAKNTV FLIEMLLPKK YHVLRFLDKG ERHPVREARAVIFFGDQEHP NVTEFAVGPL PGPCYMRALS PRPGYQSSWA SRPISTAEYA LLYHTLQEAT KPLHQFFLNT TGFSFQDCHDRCLAFTDVAP RGVASGQRRS WLIIQRYVEG YFLHPTGLEL LVDHGSTDAG HWAVEQVWYN GKFYGSPEEL ARKYADGEVDVVVLEDPLPG GKGHDSTEEP PLFSSHKPRG DFPSPIHVSG PRLVQPHGPR FRLEGNAVLY GGWSFAFRLR SSSGLQVLNVHFGGERIAYE VSVQEAVALY GGHTPAGMQT KYLDVGWGLG SVTHELAPGI DCPETATFLD TFHYYDADDP VHYPRALCLFEMPTGVPLRR HFNSNFKGGF NFYAGLKGQV LVLRTTSTVY NYDYIWDFIF YPNGVMEAKM HATGYVHATF YTPEGLRHGTRLHTHLIGNI HTHLVHYRVD LDVAGTKNSF QTLQMKLENI TNPWSPRHRV VQPTLEQTQY SWERQAAFRF KRKLPKYLLFTSPQENPWGH KRTYRLQIHS MADQVLPPGW QEEQAITWAR YPLAVTKYRE SELCSSSIYH QNDPWHPPVV FEQFLHNNENIENEDLVAWV TVGFLHIPHS EDIPNTATPG NSVGFLLRPF NFFPEDPSLA SRDTVIVWPR DNGPNYVQRW IPEDRDCSMPPPFSYNGTYR PV＜HHHHHH＞
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.