Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
Source:Recombinant protein corresponding to aa25–167 from human PD-1, fused at the C-terminus to the Fc portion of human IgG1, expressed in HEK293 cells.
Molecular Weight:~42.6kD
Assay Conditions:PD-1-PD-L1 binding activity, measured using the using the PD-1:PDL1 [Biotinylated] Inhibitor Screening BioAssay™ Kit.
Applications:Suitable for use in the study of protein-protein interaction and in vitro and in vivo protein function. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Source Antigen：Recombinant, HEK293 cells
Grade：Purified
Purity：≥90%
Form：Supplied as a liquid in PBS, pH 7.4, 20% glycerol. Labeled with Biotin.
