7-Deaza-2′-deoxyguanosine 5′-triphosphate enhances polymerase chain reaction (PCR) product yield. G residues can form secondary structures which are not fully denatured during electrophoresis. This can lead to sequence ambiguities. 7-Deaza-G doesn′t form these secondary structures, so avoids sequence ambiguities. This dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA ploymerases.
Synonyms:−N7-dGTP, 7-Deaza-dGTP
Molecular Formula:C11H17N4O13P3
Molecular Weight:506.19
Appearance:Colorless liquid
Purity:≥95%
Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
