85-6038-01　TNFRSF19L, Recombinant, Human, aa26-162, hIgG-His-Tag 50ug　532388

特徴

• RELT, also known tumor necrosis factor receptor superfamily member 19L, is one of the the tumor necrosis factor receptor superfamily. It is expressed in hematopoietic tissues and peripheral blood leukocytes. This protein mediates activation of NF-kappa-B and plays a role in T-cell activation. With overexpression of this protein in HEK-293 cells, it induces p38 and JNK signaling and activates apoptosis. And it can also costimulate T-cell proliferation in the presence of CD3 signaling.
• Source:Recombinant protein corresponding to aa26-162 from human RELT, fused to to hIgG-His-Tag at C-terminal expressed in Baculovirus.
• Molecular Weight:~41.4kD (376aa)
• Biological Activity:Measured in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 for this effect is ≤20 pg/ml.
• Endotoxin:~1EU/1ug (LAL)
• AA Sequence:STTLWQCPPG EEPDLDPGQG TLCRPCPPGT FSAAWGSSPC QPHARCSLWR RLEAQVGMAT RDTLCGDCWP GWFGPWGVPR VPCQPCSWAPLGTHGCDEWG RRARRGVEVA AGASSGGETR QPGNGTRAGG PEETAAQVEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTPEVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGKEYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDIAVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH
• Applications:Suitable for use in Bioactivity and SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.