85-6037-63　Lumican, Recombinant, Mouse, aa19-338, His-Tag 100ug　532341

特徴

• Lumican, also known as Lum, is a proteoglycan Class II member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. It is a major component of the corna, demal, and muscle connective tissues. This protein has a negatively-charged N-terminal domain containing sulfated tyrosine and disulfide bonds and ten tandem leucine-rich that repeats allowing it to bind to other extracellular components such as collagen. Lum is the major keratin sulfate proteoglycan of the cornea and is distributed in interstitial collagenous matrices throughout the body. Also, it plays a role asdefinitive link between a necessity for this protein in the development of a highly organized collagenous matrix and corneal transparency.
• Source:Recombinant protein corresponding to aa19-338 from mouse Lumican, fused to His-Tag, at C-terminal, expressed in Baculovirus.
• Molecular Weight:~37.5kD (328aa)
• Endotoxin:~1EU/1ug (LAL)
• AA Sequence:QYYDYDIPLF MYGQISPNCA PECNCPHSYP TAMYCDDLKL KSVPMVPPGI KYLYLRNNQI DHIDEKAFEN VTDLQWLILD LLENSKIK GKVFSKLKQL KKLHINYNNL TESVGPLPKS LQDLQLTNNK ISKLGSFDGL VNLTFIYLQH NQLKEDAVSA SLKGLKSLEY LDLSFNQMSK LPAGLPTSLL TLYLDNNKIS NIPDEYFKRF TGLQYLRLSH NELADSGVPG NSFNISSLLE LDLSYNKLKS IPTVNENLEN YYLEVNELEK FDVKSFCKIL GPLSYSKIKH LRLDGNPLTQ SSLPPDMYEC LRVANEITVN VEHHHHHH
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.