85-6037-14　Ephrin-A3, Recombinant, Human, aa23-214, hIgG-His-Tag 50ug　532298

特徴

• Ephrin-A3, also known as EFNA3, is a member of the ephrin family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. This protein activates EphA4 on hippocampal neurons to regulate dendritic spine morphology and long term potentiation. The same interaction induces reverse signaling through it to regulate glutamate uptake by the astrocyte and the availability of glutamate in the synapse. Astrocyte-expressed Ephrin-3 also interacts with EphA7 to inhibit the proliferation of neural progenitor cells.
• Source:Recombinant protein corresponding to aa23-214 from human Ephrin-A3 fused to hIgG-His-Tag at C-terminal expressed in Baculovirus.
• Molecular Weight:~48.7kD (434aa)
• Endotoxin:~1EU/1ug (LAL)
• AA Sequence:ADPQGPGGAL GNRHAVYWNS SNQHLRREGY TVQVNVNDYL DIYCPHYNSS GVGPGAGPGP GGGAEQYVLY MVSRNGYRTC NASQGFKRWE CNRPHAPHSP IKFSEKFQRY SAFSLGYEFH AGHEYYYIST PTHNLHWKCL RMKVFVCCAS TSHSGEKPVP TLPQFTMGPN VKINVLEDFE GENPQVPKLE KSISGLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEYKCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.