85-6037-06　CTRP5/C1qTNF5, Recombinant, Human, aa16-243, His-Tag 50ug　532288

特徴

• TRP5, also known as Complement C1q tumor necrosis factor-related protein 5, encodes a short-chain collagen which is strongly expressed in sub-retinal pigment epithelium (sub-RPE), ciliary epithelium and adiposetissue. CTRP5 is increased in mtDNA-depleted myocytes and that it stimulates the phosphorylation of AMP activated protein kinase. CTRP5 plays an important role in the adhesion of the retinal pigment epithelium(RPE) to the Bruch Membrane, and mutations are thought to impair the adhesion, resulting in sub-RPE deposits.
• Source:Recombinant protein corresponding to aa16-243 from human CTRP5, fused to His-Tag at N-terminal expressed in E. coli.
• Molecular Weight:~24.6kD (210aa)
• Endotoxin:~1EU/1ug (LAL)
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMSPPLD DNKIPSLCPG HPGLPGTPGH HGSQGLPGRD GRDGRDGAPG APGEKGEGGR PGLPGPRGDP GPRGEAGPAG PTGPAGECSV PPRSAFSAKRSESRVPPPSD APLPFDRVLV NEQGHYDAVT GKFTCQVPGV YYFAVHATVY RASLQFDLVK NGESIASFFQ FFGGWPKPAS LSGGAMVRLE PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP VFA
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.