SFTSV is a tick-borne virus that can be transmitted to humans by Haemaphysalis longicornis, a member of the Ixodidae family. H. longicornis, is endemic in the Asia-Pacific region and has a wide variety of hosts including livestock, birds, wild and domestic mammals. In some cases, animals infected with SFTSV do not exhibit clinical symptoms and are thought to act as intermediate reservoirs of the virus. Other ticks may act as vectors for SFTSV. However, bites from H. longicornis have been directly linked to cases of human SFTSV infection. Transmission of SFTSV from person-to-person has also been reported in some cases, due to contact with infected blood or mucus (Zhuang, L). In humans the clinical symptoms associated with SFTSV infection include a high fever, abdominal pain, nausea, myalgia, a dramatic reduction of platelets and leukocytes, raised serum enzyme levels and, in some cases, multi-organ failure. Fatality rates due to SFTSV infection vary between 2-30% and hospitalization may occur more frequently in the elderly and immunocompromised patients (WHO). Currently, there is no licensed prophylactic vaccine or specific antiviral treatment for SFTSV infection. SFTSV is recognized by the World Health Organization as an emerging highly pathogenic virus, which presents a significant threat to human health.
Recombinant protein corresponding to aa2-245 of Severe Fever with Thrombocytopenia Virus, S segment, Nucleoprotein, strain JP-03-Korea-13, fused to His-Tag at N-terminal, expressed in HEK293 cells.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Source Antigen：Recombinant, HEK293 cells
Grade：Highly Purified
Purity：~95%
Form：Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 500mM sodium chloride.
