85-6025-31　［取扱停止］Concanavalin A, Succinylated (Succ Con A) 25mg　518790

特徴

• Affinity purified Succinylated concanavalin A (Succ-Con A) is derived from native lectin concanavalin A (Con A). It is a nonagglutinating lectin that has a carbohydrate specificity for alphalinked mannose and glucose, with a sugar elution of alpha-methlyglucoside + alpha-methlymannoside. Succ-Con A have been studied for their effects to induce marked proliferation of human peripheral blood lymphocytes. Succ-Con A exhibits mitogenic action equal to native Con A and both increase lymphocytes levels of cyclic GMP. Unlike Con A, Succ-Con at high concertation does not decrease mitogenic activity. Succ-Con A reversibly prevents the growth of normal cells and restores a normal growth phenotype to transformed cells.
• Source:Jackbean
• Blood Specificity:None
• Sugar Specificity:alpha-Mannose, alpha-Glucose
• Inhibitory Carbohydrate:alpha-Methylmannoside + alpha-Methylglucoside
• Divalent Ions:Ca++, Mn++
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.