85-6000-50　［取扱停止］Cytotoxic T-lymphocyte Protein 4, Recombinant, Human, aa36-161, His-Tag (CTLA4) 500ug　516802

特徴

• Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
• Source:Recombinant partial protein corresponding to aa36-161 of human Cytotoxic T-lymphocyte Protein 4, fused to His-Tag at C-terminal, expressed in mammalian cell.
• Molecular Weight:~14.3kD
• Biological Activity:The ED50 as determined by its ability to bind mouse B7-1 in functional ELISA is less than 20ng/ml.
• Endotoxin:<1EU/ug (LAL).
• AA Sequence:KAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSD
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.