α-Synuclein is a major component of Parkinson’s disease aggregates and is implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders. α-Synuclein accumulates in the brains of sporadic Parkinson’s disease patients as a major component of Lewy bodies, which are intra-neuronal cytoplasmic inclusions characteristic of Parkinson’s disease. α-Synuclein appears to associate with other proteins that aggregate and is found in β-amyloid plaques and neuritic tangles in Alzheinmer’s disease. Recombinant α-Synuclein is expressed in E. coli strain and purified by column chromatography.
Recombinant protein corresponding to human Alpha Synuclein, expressed in Transformed E. coli.
Molecular Weight:~15kD
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：1mg
Source Antigen：Recombinant, E. coli, BL21DE3
Grade：Highly Purified
Purity：≥95%
Form：Supplied as a liquid in 50mM PBS, pH 7.4, 150mM NaCl, 2mM PMSF, 1mM AEBSF, 25% glycerol.
