Human S100-A9 protein also known as migration inhibitory factor-related protein 14 (MRP-14) or calgranulin-B is encoded by the S100A9 gene. S100-A9 is a member of the S100 family of proteins containing 2 EF hand calcium-binding motifs. This protein may function in the inhibition of casein kinase. MRP-14 complexes with MRP-8 (S100A8), another member of the S100 family of calcium-modulated proteins; together, MRP-8 and MRP-14 regulate myeloid cell function by binding to Toll-like receptor-4 (TLR-4) and the receptor for advanced glycation end products.
Recombinant protein corresponding to 114aa of human Calprotectin (S100A9), fused to 6xHis-Tag, expressed in Transformed E. coli.
Molecular Weight:~13-15kD
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:1mg
Source Antigen:Recombinant, E. coli, BL21DE3
Grade:Highly Purified
Purity:≥95%
Form:Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 150mM NaCl, 2mM PMSF, 25% glycerol.