Rift Valley Fever Virus Nucleoprotein has been manufactured in response to the unmet need for highly purified, concentrated protein for use in serological based diagnostic assays. Rift Valley Fever Virus nucleoprotein is engineered in human cells using state-of-the-art expression and purification techniques.
Rift Valley fever (RVF), is an emerging zoonotic, mosquito-borne viral disease that primarily affects livestock but can also affect humans. The disease causes significant loss to livestock and severe illness and death in humans, having a significant economic impact in countries where RVF is prevalent.
RVF is caused by the Rift Valley fever virus (RVFV), which was first recognised in the 1930s in the Rift Valley region of Kenya. Rift Valley fever virus is an enveloped RNA virus that belongs to the genus Phlebovirus, which is a member of the Bunyaviridae family of viruses. It is an arthropod-borne virus that is transmitted to domesticated livestock by mosquitoes. Several species of mosquito transmit RVFV, and the vector varies according to the geographical region. Cattle, sheep, goats, and camels are particularly susceptible to RVF and serve as amplifying hosts for the virus. Reports of RVFV outbreaks outside sub-Saharan Africa have raised concerns that RVFV may spread to temperate climates through emerging competent vectors.
Humans may become infected through contact, via open wounds, with blood products, organs and bodily fluids from animals infected with RVFV. In some cases, humans may be infected through the bite of infected mosquitoes, but this is uncommon. Human to human transmission of RVFV as not been reported to date (Pepin M, et al).
Source:Recombinant protein corresponding to aa2-245 of Rift Valley Fever Virus segment Nucleoprotein, fused to 6xHis-Tag at N-terminal via a 10aa glycine-serine linker, expressed in HEK293 cells.
Strain:ZH-548
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Source Antigen：Recombinant, HEK293 cells
Grade：Highly Purified
Purity：~95% (SDS-PAGE)
Form：Supplied as a liquid in 20mM TRIS, pH 8.0, 10mM sodium chloride.
