Human herpes simplex virus (HSV), also known as human herpes virus (HHV), is a large enveloped double stranded DNA virus that belongs to the Herpesviridae family, subfamily Alphaherpesvirinae. Human HSV exists as two distinct serotypes, herpes simplex virus type -1 (HSV-1) and type -2 (HSV-2). Both HSV-1 and HSV-2 are neurotrophic viruses that invade the central nervous system (CNS), where they replicate, and have the capacity to establish a latent infection (Nicoll, MP et al).
HSV-1 and HSV-2 are primarily transmitted from human-to-human through contact with mucosal surfaces and damaged skin, which are common sites of primary HSV infection. However, the route and site of infection differs for each serotype with some reported overlap. Typically, HSV-1 is transmitted through oral-to-oral contact giving rise to infection in the lips, eyes and oropharyngeal mucosa but HSV-1 infection can also occur in the genital tract through oral-genital contact. HSV-2 tends to be sexually transmitted via contact with infected mucosa or damaged skin associated with the genital tract. In most cases, individuals infected with either HSV-1 or HSV-2 for the first time remain asymptomatic or present with painful blisters or ulcers at the site of infection.
Description:A high concentration of native HSV-2 particles and proteins from a clarified crude lysate
Inactivation:0.1% Triton x-100.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1ml
Source Antigen：Native HSV-2 particles and proteins from a clarified crude lysate
Grade：Lysate
Purity：Lysate
Form：Supplied as a liquid in PBS, 0.1% Triton x-100.
