Human Adenoviruses (HAdV) are non-enveloped, non-segmented double stranded DNA viruses, which belong to the genus Mastadenovirus within the Adenoviridae family of viruses. Human adenoviruses commonly cause respiratory disease but some HAdV serotypes cause gastrointestinal disease, conjunctivitis and cystitis. The clinical disease caused by HAdV infection varies depending on the HAdV type. In immunocompromised patients, HAdV infection can cause severe clinical symptoms that may lead to respiratory failure, neurological disease and death (CDC).
Adenovirus type 40 hexon protein is a major component of the adenovirus capsid. The individual hexon protein is a complex molecule of approximately 100kD, which is comprised of a pedestal region and three loops that project away from the surface of the virion. Hexon proteins readily form trimers, and can then further self-assemble into capsomeres of 240 hexons.
Description:Purified native hexon protein from Adenovirus 40. Hexon is the major Adenovirus capsid protein. It is present as 240 copies which form 20 facets of the icosahedral capsid. Hexon antigen is generated from functional Ad40 particles produced in tissue culture.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Source Antigen：Tissue Culture
Grade：Highly Purified
Purity：≥95% (SDS-PAGE)
Form：Supplied as a liquid in in 10mM Bis Tris Propane, pH 7.2, 375mM sodium chloride, 0.09% sodium chloride.
