85-5998-52　HLA-DRB1, Recombinant, Human, aa30-227, His-Tag (Major Histocompatibility Complex, Class II, DR beta 1, HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, SS1) 50ug　506178

特徴

• HLA-DRB1, also known as major histocompatibility complex, class II, DR beta 1 precursor, belongs to the human leukocyte antigen (HLA) class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins to T helper cells. It helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria. It is associated with an increased incidence of rheumatoid arthritis.
• Description:Recombinant protein corresponding to aa30-227 of human HLA-DRB1, fused to His-tag at C-terminus, expressed in Baculovirus
• Molecular Weight:~24kD (207aa), ~28-40kD (SDS-PAGE under reducing conditions)
• Endotoxin:<1EU/1ug (LAL)
• AA Sequence:ADPGDTRPRF LWQPKRECHF FNGTERVRFL DRYFYNQEES VRFDSDVGEF RAVTELGRPD AEYWNSQKDI LEQARAAVDT YCRHNYGVVE SFTVQRRVQP KVTVYPSKTQ PLQHHNLLVC SVSGFYPGSI EVRWFLNGQE EKAGMVSTGL IQNGDWTFQT LVMLETVPRS GEVYTCQVEH PSVTSPLTVE WRARSESAQS KHHHHHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.