Thyrotropic hormone or Thyroid stimulating hormone (TSH) belongs to glycoprotein hormone family. The product can enhance vascular endothelial growth factor (VEGF) secretion and angiogenesis in thyroid cancer cell lines. Two-chain glycoprotein hormone. The α-chain is not active, biological specificity attributed rather to the β-chain. Activates adenylate cyclase in the thyroid gland, stimulating iodine uptake, thyroxine synthesis and release. Goitrogenic.
Thyrotropic hormone from bovine pituitary can be used for TSH stimulation test for assessing the thyroid gland function after NTI induction. The product was injected in 4-week-old male C57BL/6J and CBA/N mice for studying the thyrotropin involvement in photoperiodic signal transduction.
Source:Bovine Pituitary Gland
Synonyms:TSH; Thyroid stimulating hormone; Thyrotropin from bovine pituitary glands
Appearance:Supplied as a lyophilized powder. Contains phosphate buffer salts.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Source Antigen：Bovine Pituitary Gland
Grade：Highly Purified
Purity：Highly purified
Form：Supplied as a lyophilized powder. Contains phosphate buffer salts.
