CD8B, also known as T-cell surface glycoprotein CD8 beta chain isoform 5, is a cell surface transmembrane glycoprotein. This protein serves as a co-receptor for the T cell receptor (TCR). It found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-alpha and CD8-beta chain. Both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. Recombinant human CD8B, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
Source:Recombinant protein corresponding to aa22-170 from human CD8B, fused to His-Tag at C-terminal, expressed in Insect Cell.
Molecular Weight:~17.8kD (158aa)~18-28kD (SDS-PAGE under reducing conditions)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:20ug
Source Antigen:Recombinant, Insect Cell
Grade:Purified
Purity:~85% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 10% glycerol.