85-5958-41　β-Nicotinamide-d4 Mononucleotide (d4-major) 10mg　CAS No:1094-61-7　469744

特徴

• β-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
• Synonyms:3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium-d4 Inner Salt
• Molecular Formula:C₁₁H₁₁D₄N₂O₈P
• Molecular Weight:338.24
• Appearance:White to off-white solid
• Purity:≥95%
• Melting Point:>113°C (dec.)
• Solubility:Methanol (Slightly), Water (Slightly)
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.