SMAD3 Inhibtor, SIS 3-d3 is the labeled analogue of SMAD3 Inhibtor, SIS 3 (S564500), which selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.
Molecular Formula:C28H24D3N3O3
Molecular Weight:456.55
Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.