85-5867-44　Rimacalib 5mg　464725

特徴

• Rimacalib, a inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib. The IC50s of Rimacalib are ~1uM for CaMKIIα to ~30uM for CaMKIIγ.
• Synonyms:SMP 114; N-[3-[(1S)-1-(2-Fluoro[1,1'-biphenyl]-4-yl)ethyl]-5-isoxazolyl]-4-morpholinecarboximidamide
• Molecular Formula:C₂₂H₂₃FN₄O₂
• Molecular Weight:394.44
• Appearance:Supplied as a off-white to pale orange solid
• Purity:≥99%
• Melting Point:>56°C (dec.)
• Solubility:Chloroform (Slightly), Methanol (Slightly), DMSO (125mg/ml)
• Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：5mg
• Grade：Highly Purified
• Purity：≥99%
• Form：Supplied as a off-white to pale orange solid
• Molecular Formula：C₂₂H₂₃FN₄O₂
• Molecular Weight Non Ab：394.44
• EU Commodity Code：38220090
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