ONO 5334 is a novel cathepsin K inhibitor. Inhibited bone resorption in human osteoclast and reduced calcium level increased by PTHrP in thyroparathyroidectomized rat and decreased serum and urine C-telopeptide of type I collagen level in monkey. Values in postmenopausal patient with osteoporosis, increases lumbar spine, total hip and femoral neck bone minerals.
Molecular Formula:C21H34N4O4S
Molecular Weight:438.58
Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
