Metanicotine-d3 is the isotope labelled analog of Metanicotine (M321250); an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer’s type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors.
Molecular Formula:C10H11D3N2
Solubility:Chloroform, Methanol
Molecular Weight:165.25
Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.