m-Toluenesulfonyl Chloride was used as a reagent in the synthesis of sulfone hybrid scaffolds which displayed β-glucuronidase inhibitory potential. Also used in the synthesis of arylmenthols via radical arylation of isopulegol. m-Toluenesulfonyl chloride may be used in the synthesis of mesityl-m-tolyl sulfone via reaction with mesitylene.
Reactant involved in they synthesis of biologically active molecules including:
Small molecule ligands for the Stat3 SH2 domain
Isoindoline-5-propenehydroxamates for use as histone deactylase inhibitors
Phenyl-pyrazolylamine-based derivatives as FLT3 kinase inhibitors
Aryldisulfonamides with antibacterial activity
Quinazoline analogs for the treatment of Gaucher disease
17β-HSD2 inhibitors for the treatment of osteoporosis
Storage and Stability:Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic, keep under inert atmosphere.
