Estrone 4-O-β-D-Glucuronide Methy Ester Triacetate is an intermediate in the synthesis of 4-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt, which is a glucuronide derivative of 4-Hydroxy-17β-estradiol; a metabolite of Estradiol which is the major estrogen secreted by the premenopausal ovary.