Cucurbitacin I (cas# 2222-07-3) is a useful research chemical
Cucurbitacin I is a selective Janus Kinsase (JAK)/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. It suppressed the levels of phosphotyrosine STAT3 in v-Src-transformed NIH 3T3 cells and human cancer cells potently and rapidly.
Molecular Formula:C30H42O7
Molecular Weight:514.65
Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.