CK 1827452-d8 is the labeled analogue of CK 1827452 (C544000), a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction.
Molecular Formula:C20H16D8FN5O3
Molecular Weight:409.48
Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
