85-5364-22　5,6-Dihydrouridine 5mg　CAS No:5627-05-4　437195

特徴

• 5,6-Dihydrouridine is an intermediate used in the synthesis of 3,4,5,6-Tetrahydrouridine which is a derivative of Uridine.Tetrahydrouridine (THU) is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA.
• Synonyms:Dihydro-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Dihydrouridine; 1-β-D-Ribofuranosyl-hydrouracil
• Molecular Formula:C₉H₁₄N₂O₆
• Molecular Weight:246.22
• Purity:≥96%
• Appearance:White to off-white solid
• Method for Determining Identity:Proton NMR and Mass Spectrometric Analysis
• TLC Conditions:SiO2; Dichloromethane: Methanol=8:2 Visualized with UV and AMCS; Single Spot, Rf=0.45
• Elemental Analysis:Calculated: %C: 43.90, %H: 5.73, %N: 11.38
• Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• Specific Rotation:As reported
• Storage and Stability:Store at 4°C under inert atmosphere. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap