4',7-Bis(benzyloxy)-5-hydroxy-flavone is an intermediate in synthesizing Apigenin 5-O-β-D-Glucuronide, a metabolite of Apigenin. Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells.
Molecular Formula:C29H22O5
Solubility:DMF (Slightly), DMSO (Slightly)
Molecular Weight:450.48
Storage and Stability:Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
