Calcineurin is a kind of serine/threonine protein phosphatase regulated by Ca2+/camodulin, which exists widely in tissue cells of mammals. As an effector molecule of Ca2+ downstream signal, calcineurin participates in the regulation of numerous cell functions. It plays a role in regulating the signal transduction of T cells activation as well as the release and synaptic plasticity of neurotransmitter. Recent studies show that CaN plays a central role in the occurrence and development of cardiac hypertrophy.
Sample Type:Animal tissues, cells
Intended Use:This kit can be used for detection of calcineurin (CaN) activity in samples, such as animal tissues, cells, etc.
Storage and Stability:Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Kit Components (see Protocol for final kit quantities)
