The West Nile Virus NS1 protein is a native hexameric presentation. The hexamer is believed to be the biologically active form of NS1 involved in key aspects of West Nile Fever pathogenesis. The resultant West Nile Virus NS1 protein is purified to a high degree, is in its native folding state, and possesses all post-translational modifications. This advanced approach results in a product which delivers optimal antigenicity by virtue of its human origin. The West Nile Virus NS1 Protein has been manufactured in response to the unmet need for a highly purified, concentrated protein for use in further vaccine development and serological based diagnostic assays. The detection of the NS1 protein offers much higher fidelity across multiple flaviviruses where cross-reactivity can otherwise pose an issue.
Recombinant protein corresponding to Strain NY99 of West Nile Virus -NS1, fused to 6X His-Tag at C-terminal, expressed in 293 human cells
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.