UBE2D2, also known as Ubiquitin-conjugating enzyme E2 D2, is a member of the E2 ubiquitin- conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. UBE2D2 catalyzes ubiquitination of IkB-alpha in a phosphorylation and SCFB-TRCP dependent manner. Recombinant human UBE2D2, expressed in E. coli and purified by using conventional chromatography techniques.
Source:Recombinant protein corresponding to aa1-147 of human UBE2D2, expressed in E. coli.
Molecular Weight:~16.7kD (147aa), Confirmed by MALDI-TOF
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Source Antigen:Recombinant, E. coli
Grade:Highly Purified
Purity:~95% (SDS-PAGE)
Form:Supplied as a liquid in 20mM MES, pH 6.0, 1mM DTT, 50mM sodium chloride.