85-4781-88　TPSAB1, Recombinant, Human, aa31-275, His-Tag (Tryptase Alpha/Beta-1, TPSAB1, TPS1, TPS2, TPSB1) 50ug　396939

特徴

• TPSAB1, also known as tryptase alpha/beta-1, is a serine protease with trypsin-like specificity. It is the key neutral protease present in mast cells and is discharged upon the coupled activation-degranulation response of this cell type. This protein is enzymatically active only as a heparin-stabilized tetramer, and is resistant to all known endogenous proteinase inhibitors. Also, it is implicated as a mediator in the pathogenesis of asthma and other allergic and inflammatory disorders. Recombinant human TPSAB1, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
• Source:Recombinant protein corresponding to aa31-275 of human TPSAB1, fused to His-Tag at C-terminal, expressed in insect cell.
• Molecular Weight:~28.2kD (251aa), ~28-40kD (SDS-PAGE under reducing conditions)
• Endotoxin:<1EU/1ug (determined by LAL method)
• AA Sequence:IVGGQEAPRS KWPWQVSLRV HGPYWMHFCG GSLIHPQWVL TAAHCVGPDV KDLAALRVQL REQHLYYQDQ LLPVSRIIVH PQFYTAQIGA DIALLELEEP VNVSSHVHTV TLPPASETFP PGMPCWVTGW GDVDNDERLP PPFPLKQVKV PIMENHICDA KYHLGAYTGD DVRIVRDDML CAGNTRRDSC QGDSGGPLVC KVNGTWLQAG VVSWGEGCAQ PNRPGIYTRV TYYLDWIHHY VPKKPHHHHH H
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.