85-4781-82　TNFRSF10A, Recombinant, Human, aa24-239, His-Tag (Tumor Necrosis Factor Receptor Superfamily Member 10A, APO2, CD261, DR4, TRAILR-1, TRAILR1) 50ug　396935

特徴

• TNFRSF10A, also known as tumor necrosis factor receptor superfamily member 10A, is a cell surface receptor of the TNF-receptor superfamily that binds TRAIL. This receptor is activated by tumor necrosis factor- related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Recombinant human TNFRSF10A, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
• Source:Recombinant protein corresponding to aa24-239 of human TNFRSF10A, fused to His-Tag at C-terminal, expressed in insect cell.
• Molecular Weight:~23.9kD (224aa), ~18-28kD (SDS-PAGE under reducing conditions)
• Endotoxin:<1EU/1ug (determined by LAL method)
• AA Sequence:ASGTEAAAAT PSKVWGSSAG RIEPRGGGRG ALPTSMGQHG PSARARAGRA PGPRPAREAS PRLRVHKTFK FVVVGVLLQV VPSSAATIKL HDQSIGTQQW EHSPLGELCP PGSHRSEHPG ACNRCTEGVG YTNASNNLFA CLPCTACKSD EEERSPCTTT RNTACQCKPG TFRNDNSAEM CRKCSRGCPR GMVKVKDCTP WSDIECVHKE SGNGHNLEHH HHHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.