85-4781-70　SELL, Recombinant, Human, aa52-345, His-Tag (L-Selectin, SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1) 50ug　396925

特徴

• SELL, also known as L-selectin, is a cell surface component that is a member of a family of adhesion/homing receptors that play important roles in lymphocyte-endothelial cell interactions. This protein mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naïve and effector subsets such as regulatory T cells. Importantly, this protein has been shown to have both adhesive and signaling functions during leukocyte migration. Recombinant human SELL, fused to His-tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
• Recombinant protein corresponding to aa52-345 of human SELL, fused to His-tag at C-terminal, expressed in insect cell. Accession: NP_000646
• Molecular Weight:~34.1kD (303aa), ~40-57kD (SDS-PAGE under reducing conditions)
• AA Sequence:ADPWTYHYSE KPMNWQRARR FCRDNYTDLV AIQNKAEIEY LEKTLPFSRS YYWIGIRKIG GIWTWVGTNK SLTEEAENWG DGEPNNKKNK EDCVEIYIKR NKDAGKWNDD ACHKLKAALC YTASCQPWSC SGHGECVEII NNYTCNCDVG YYGPQCQFVI QCEPLEAPEL GTMDCTHPLG NFSFSSQCAF SCSEGTNLTG IEETTCGPFG NWSSPEPTCQ VIQCEPLSAP DLGIMNCSHP LASFSFTSAC TFICSEGTEL IGKKKTICES SGIWSNPSPI CQKLDKSFSM IKEGDYNHHH HHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.