85-4781-50　Mydgf, Recombinant, Mouse, aa25-166, His-Tag (Myeloid-Derived Growth Factor, Il25, Ly6elg) 10ug　396909

特徴

• Mydgf, also known as Myeloid-derived growth factor, is a bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and repair after myocardial infarction. It stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Mydgf-deficient mice develop larger infarct scars and more severe contractile dysfunction compared to wild-type mice. Recombinant mouse Mydgf, fused to His-Tag at N-terminal, expressed in E. coli and purified by using conventional chromatography techniques.
• Source:Recombinant protein corresponding to aa25-166 of mouse Mydgf, fused to His-Tag at N-terminal, expressed in E. coli.
• Molecular Weight:~18.1kD (165aa), Confirmed by MALDI-TOF
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSVSEPTTV PFDVRPGGVV HSFSQDVGPG NKFTCTFTYA SQGGTNEQWQ MSLGTSEDSQ HFTCTIWRPQ GKSYLYFTQF KAELRGAEIE YAMAYSKAAF ERESDVPLKS EEFEVTKTAV SHRPGAFKAE LSKLVIVAKA ARSEL
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.