MS4A1, also known as B-lymphocyte antigen CD20, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase and progressively increasing in concentration until maturity. It is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It plays a role in the microenvironmental interactions of B cells. This structurally unique phosphoprotein plays a role in the regulation of human B cell proliferation and differentiation. It was strongly phosphorylated on resting B cells after CDw40 stimulation, suggesting that it may be functionally regulated by a protein kinase. Recombinant human MS4A1, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
Source:Recombinant protein corresponding to aa210-297 of human MS4A1, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~11.1kD (97aa), ~18-28kD (SDS-PAGE under reducing conditions)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：10ug
Source Antigen：Recombinant, Insect cell
Grade：Highly Purified
Purity：~90% (SDS-PAGE)
Form：Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
