85-4780-87　Crygd, Recombinant, Mouse, aa1-174, His-Tag (Gamma-Crystalin D, Aey4, Cryg-1, DGcry-1, Lop12) 500ug　396855

特徴

• Crygd, also known as gamma-crystalin D, belongs to the beta/gamma-crystallin family. Crystallins are the dominant structural components of the vertebrate eye lens. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Gamma-crystallins have been involved in cataract formation. Defects in Crygd are a cause of cataract autosomal dominant (ADC), cataract congenital non-nuclear polymorphic autosomal dominant (CCP), cataract congenital cerulean type 3 (CCA3) and cataract crystalline aculeiform (CACA). Recombinant mouse Crygd protein, fused to His-Tag at N-terminal, was expressed in E. coli and purified by using conventional chromatography techniques.
• Source:Recombinant protein corresponding to aa1-174 of mouse Crygd, fused to His-Tag at N-terminal, expressed in E. coli.
• Molecular Weight:~23.5kD (197aa), Confirmed by (MALDI-TOF)
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSMGKITFY EDRGFQGRHY ECSTDHSNLQ PYFSRCNSVR VDSGCWMLYE QPNFTGCQYF LRRGDYPDYQ QWMGFSDSVR SCRLIPHAGS HRIRLYEREE YRGQMIEFTE DCPSLQDRFH FNEIYSLNVL EGCWVLYDMT NYRGRQYLLR PGEYRRYHDW GAMNARVGSL RRVMDFY
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.