CD58, also known as lymphocyte function-associated antigen 3 isoform 1, is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. It is an important regulator of immune cell function which occurs as both surface-associated and soluble forms. It is associated with increased risk for multiple sclerosis. Recombinant human CD58, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
Source:Recombinant protein corresponding to aa29-215 of human CD58, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~22.5kD (196aa), ~28-40kD (SDS-PAGE under reducing conditions)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Source Antigen：Recombinant, Insect cell
Grade：Highly Purified
Purity：~95% (SDS-PAGE)
Form：Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
