CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
Source:Recombinant protein corresponding to aa52-164 of human CD247, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~14.1kD (122aa), ~13.5-18kD (SDS-PAGE under reducing conditions
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：20ug
Source Antigen：Recombinant, Insect cell
Grade：Highly Purified
Purity：~90% (SDS-PAGE)
Form：Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 1mM DTT, 1mM EDTA, 0.1M sodium chloride, 50% glycerol.
