CD163, also known as scavenger receptor cysteine-rich type 1 protein M130 isoform a, is a scavenger receptor for the hemoglobin-haptoglobin complex that is essential in liver, spleen and circulation. This protein is generated by ectodomain shedding of the membrane bound receptor. Also, it is upregulated in a large range of inflammatory diseases including liver cirrhosis, macrophage activation syndrome, HIV infection and sepsis. Recombinant human CD163, fused to His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques.
Source:Recombinant protein corresponding to aa42-1050 of human CD163, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~109.8kD (1015aa), ~100kD over (SDS-PAGE under reducing conditions.)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.