85-4780-59　Ak2, Recombinant, Mouse, aa1-239, His-Tag (Ak-2, Adenylate Kinase 2 Mitochondrial Isoform A) 20ug　396828

特徴

• Ak2, also known as Adenylate kinase 2 mitochondrial isoform a, is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (Ak1, Ak2 and Ak3) are characterized in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Ak2 is localized in the mitochondrial intermembrane space and may pay a role in apoptosis.
• Source:Recombinant protein corresponding to aa1-239 of mouse Ak2, fused to His-Tag at N-terminal, expressed in E. coli.
• Molecular Weight:~29kD (263aa), Confirmed by MALDI-TOF
• Endotoxin:<1EU/1ug (determined by LAL method)
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMAPNVL ASEPEIPKGI RAVLLGPPGA GKGTQAPKLA ENFCVCHLAT GDMLRAMVAS GSELGKKLKA TMDAGKLVSD EMVVELIEKN LETPSCKNGF LLDGFPRTVR QAEMLDDLME KRKEKLDSVI EFSIQDSLLI RRITGRLIHP KSGRSYHEEF NPPKEPMKDD ITGEPLIRRS DDNEKALKTR LEAYHTQTTP LVEYYRKRGI HCAIDASQTP DIVFASILAA FSKATCKDLV MFI
• Specific Activity:>40units/mg. One unit will convert 2umoles of ADP to ATP + AMP/minute at pH 7.5 at 37°C.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.