Pure Maclura pomifera oil (MPA) from Osage Orange.
Maclura pomifera contains an agglutinin, a lectin, that is highly specific toward the T-antigen.[2] Osajin and pomiferin are flavonoid pigments present in the wood and fruit, comprising about 10% of the fruit's dry weight. The plant also contains the flavonol morin. Primary components of fresh fruit include pectin (46.04%), resin (16.64%), fat (5.16%), and sugar (before hydrolysis, 4.46%). Alkaloids, glucosides, titratable acids, and vitamin C are also present. Moisture content of fresh fruits is about 80%.[3]
Lectins are derived from the extracts of plants, animals, viruses and microorganisms and are known to agglutinate red blood cells. These agglutinins can select cell types according to blood group activities utilizing sugar-binding mechanisms.
Lectins form precipitates with glycoconjugates and are useful for identifying or separating oligosaccharides with identical sugar compositions such as galactose, mannose or glucose.
Inhibitory Carbohydrate:Not inhibited by simple sugars at < 50mM. Lactose and Sialic acidwill exhibit some inhibitory potency at concentrations greater than 75mM. Sialyllactose alpha (2, 6) is the most potent inhibitor of leukoagglutination.
Activity:Less than 5ug/ml will agglutinate type O human erythrocytes. Less than 0.1ug/ml will agglutinate neuraminidase treated cells.
