TACSTD2, also known as tumor-associated calcium signal transducer 2, is an identified cell surface glycoprotein highly expressed by human carcinomas. It is detected in normal kidney, lung, ovary and testis, similarly to the human gene. It is undetectable in undifferentiated spindle cell carcinomas, this suggests a preferential expression at early stages of tumor progression. Its inhibition suppresses the proliferation and invasion of laryngeal carcinoma cells via the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway.
Source:Recombinant protein corresponding to aa31-274 from human TACSTD2, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~28.6kD (253aa), 28-40kD (SDS-PAGE under reducing conditions)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Source Antigen:Recombinant, Baculovirus
Grade:Highly Purified
Purity:~95% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 10% glycerol.