85-4741-90　SLAMF6, Recombinant, Human, aa22-226, His-Tag (SLAMF Family Member 6 Isoform 1, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000) 50ug　377974

特徴

• SLAMF6, also known as SLAM family member 6 isoform 1, belongs to the SLAM family of immune cell receptors. It is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28- independent manner. This protein is expressed on NK-, T-, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation.
• Source:Recombinant protein corresponding to aa22-226 from human SLAMF6 protein, fused to His-Tag at C-terminal, expressed in insect cell.
• Molecular Weight:~24.1kD (214aa), 28-40kD (SDS–PAGE under reducing conditions.)
• Endotoxin:<1EU/1ug (determined by LAL method)
• AA Sequence:ADPQSSLTPL MVNGILGESV TLPLEFPAGE KVNFITWLFN ETSLAFIVPH ETKSPEIHVT NPKQGKRLNF TQSYSLQLSN LKMEDTGSYR AQISTKTSAK LSSYTLRILR QLRNIQVTNH SQLFQNMTCE LHLTCSVEDA DDNVSFRWEA LGNTLSSQPN LTVSWDPRIS SEQDYTCIAE NAVSNLSFSV SAQKLCEDVK IQYTDTKMHH HHHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.