SH2D1B, also known as SH2 domain-containing protein 1B, is one of the proteins which activate NK cells. It plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. Two isoforms of the human protein are produced by alternative splicing.
Source:Recombinant protein corresponding to aa1-132 from human SH2D1B, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~16.4kD (141aa), 18-28kD (SDS-PAGE under reducing conditions.)
Endotoxin:<1EU/1ug (determined by LAL method)
AA Sequence:ADPMDLPYYH GRLTKQDCET LLLKEGVDGN FLLRDSESIP GVLCLCVSFK NIVYTYRIFR EKHGYYRIQT AEGSPKQVFP SLKELISKFE KPNQGMVVHL LKPIKRTSPS LRWRGLKLEL ETFVNSNSDY VDVLPHHHHH H
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Source Antigen:Recombinant, Baculovirus
Grade:Highly Purified
Purity:~90% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 20% glycerol.