SDC2, also known as syndecan 2, is a conserved family of heparan- and chondroitin-sulfate carrying transmembrane protein. It is a cell membrane proteoglycans that can modulate the activity and dynamics of some growth factor receptors and integrins. It is expressed in hepatic stellate cells (HSCs), a key cell type involved in matrix deposition in liver fibrotic disorders. It has been implicated in the formation of specialized membrane domains and functions as a direct link between the extracellular environment and the organization of the cortical cytoplasm.
Source:Recombinant protein corresponding to aa19-144 from human SDC2, fused to His-Tag at C-terminal, expressed in insect cell.
Molecular Weight:~15kD (135aa), 18-28kD (SDS-PAGE under reducing conditions)
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:10ug
Source Antigen:Recombinant, Baculovirus
Grade:Highly Purified
Purity:~90% (SDS-PAGE)
Form:Supplied as a liquid in PBS, pH 7.4, 10% glycerol.